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291 Assessment of mobility and related factors among older patients with osteoporosis / Tran Viet Luc, Nguyen Thi Thu Huong, Nguyen Trung Anh // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 24-31 .- 610

This cross-sectional study was conducted to assess mobility and related factors among older people with osteoporosis treated at the National Geriatric Hospital. Mobility was assessed using the Time Up and Go test (TUG test).

292 Factors related to risk of falls among older post-stroke patients / Tran Viet Luc, Nguyen Trung Anh, Nguyen Thi Thu Huong // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 32-38 .- 610

This study was conducted to identify factors related to fall risk among older post-stroke patients. A cross-sectional study was conducted on 107 post-stroke patients aged ≥ 60 years old treated at the National Geriatric Hospital. Fall risk was assessed using the 21-item Fall Risk Index. This study showed two in three participants have a high risk of falls. Disability levels, instrumental activities of daily living, and depression were associated with a high risk of falls.

293 Lower limb strength and associated factors among older patients with dementia / Tran Viet Luc, Nguyen Trung Anh, Nguyen Thi Thu Huong // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 39-47 .- 610

This cross-sectional study was conducted to assess lower limb strength and related factors among older people with dementia examined and treated at the National Geriatric Hospital. Lower limb strength was assessed using the 30-Second Chair Stand Test.

294 Clinical, subclinical characteristics and treatment outcomes of patients with community - acquired pneumonia at risk of pes infection / Dang Duy Thanh, Cao Thi My Thuy, Nguyen Thi Hong Tran, Truong Thi Nhu Hao, Vo Nhat Khoa, Nguyen Vu Hien, Nguyen The Bao // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 48-56 .- 610

This study aims to describe the clinical and subclinical characteristics and evaluate treatment outcomes of community-acquired pneumonia (CAP) patients at risk of Pseudomonas aeruginosa, extended-spectrum beta-lactamases-producing Enterobacteriaceae, methicillin-resistant Staphylococcus aureus (PES) infection. A cross-sectional descriptive study was conducted on 90 CAP patients with potential PES infection admitted to the Respiratory Department of Can Tho Central General Hospital in 2023.

295 Factors that related with sleep disturbance among older nursing home residents with dementia / Tran Viet Luc, Nguyen Xuan Thanh, Nguyen Ngoc Tam, Vu Thi Thanh Huyen // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 57-63 .- 610

This study aimed to identify factors that related with sleep disturbance among older people with dementia in nursing homes. This cross-sectional study included 140 participants aged 60 years old and over, who were diagnosed with dementia (according to DSM 5 criteria) from November 2022 through January 2023 in 3 nursing homes in Hanoi, Vietnam. Sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI) questionnaire.

296 Nutritional status in older patients with parkinson’s disease and associated factors / Tran Viet Luc, Nguyen Ngoc Tam, Nguyen Trung Anh // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 64-73 .- 610

This study was conducted to assess factors related to the nutrition status among older patients with Parkinson’s disease (PD) in 2023. A cross-sectional study was conducted on participants aged over 60 years old having PD at the National Geriatric Hospital from February 2023 to October 2023. The nutritional status was assessed using Mini Nutritional Assessment Short Form (MNA – SF) questionnaires.

297 Serum vascular endothelial growth factor levels and some characteristics of diabetic retinopathy patients / Vu Van Nga, Nguyen Thi Binh Minh, Dinh Thi My Dung, Nguyen Thi Lan Anh, Hoang Thi Thu Ha, Le Thi Minh Phuong, Do Thi Le Hang, Do Thi Quynh, Pham Thi Thuy An, Le Ngoc Thanh, Tran Van Khanh, Vu Thi Thom // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 74-82 .- 610

Diabetic retinopathy (DR) is a dangerous microvascular complication of diabetes mellitus (DM). The escalating prevalence of diabetes increases the rate of DR patients in Vietnam. Numerous studies have indicated that serum vascular endothelial growth factor (VEGF) can be used as a marker for monitoring the progression of this disease. Our study included 150 diabetic patients and 75 healthy individuals in the control group. Our study included 150 diabetic patients and a control group of 75 healthy individuals. We investigated the association between serum VEGF levels and some characteristics in diabetic retinopathy patients. Clinical data (pulse, blood pressure, medical history, and body mass index) and paraclinical data (Glucose, HbA1c) were collected. Serum samples were analyzed to determine VEGF concentrations. Our study fond that serum VEGF levels were higher in the group with DR compared to the other two groups and exhibited a correlation with glucose levels in diabetic patients (p < 0.05).

298 Prevalence and associated factors of gestational diabetes mellitus: A multicenter, cross-sectional study in mekong delta region / Tran Khanh Nga, Cao Ngoc Thanh, Pham Van Linh, Vo Thi Anh Trinh // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 83-90 .- 610

The purpose of this study was to determine the prevalence and associated factors of gestational diabetes mellitus (GDM) in the Mekong Delta region. A multicenter, cross-sectional descriptive study was conducted on 1727 pregnant women undergoing oral glucose tolerance testing (OGTT) at 4 major central hospitals of 4 provinces in the Mekong Delta region from 06/2017 to 06/2022.

299 Bronchopulmonary dysplasia in extremely preterm infants: Prevalence and related factors / Nguyen Thi Van, Tran Dieu Linh, Le Minh Trac // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 91-97 .- 610

Infants born extremely preterm are defined as a birth under 28 weeks gestational age. Bronchopulmonary dysplasia (BPD) is the most common lung complication in this population and manyfactors can contribute to the development of BPD. The objective of this study was to identify the prevalence of BPD and to analyse the related factors of BPD in extremely preterm infants. Seventy two infants who met the inclusion criteria were included in the study. BPD was diagnosed according to Jobe and Bancalari definition. The prevalence of BPD was 79.2%. There was an inverse relationship between the percentage of BPD, the severity of BPD and the gestational age and birth weight. Invasive ventilation requirement of more than 7 days was the independent factor of BPD.

300 Evaluation of antitumor activity of saphia alkali K90 on dmba-induced carcinogenesis in swiss mice / Pham Thi Van Anh, Nguyen Phuong Dung, Mai Phuong Thanh // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 106-114 .- 610

The present study aimed to initially evaluate the anti-tumor effect of orally administered Saphia Alkali K90 in 7,12-dimethylbenz(a)anthracene (DMBA)-induced carcinogenesis in Swiss mice. Mice exposed to DMBA (total dose of 6 mg, p.o.) were treated with SAK90 at 15 ml/kg BW and 45 ml/kg BW daily. The vehicle was given to both normal and diseased controls. The change in body weight, mortality rate, tumor incidence, tumor burden, tumor yield, histopathology, and hematological and biochemical parameters were evaluated after 16 weeks of treatment.