Tóm tắt:

Resumed the way T-cells are regulated between active and inactive states. The discovery of two receptors for the transduction of inhibitory signals, the cytotoxic T-cell receptor and the programmed cell death receptor, is presented in the second part. Disrupting the backward process of Tcells by blocking these receptors triggers the actions of T-cells against cancer cells and brings hope for cancer patients. In the third section, we discussed the developments of three groups of antibodies for anti-cancer purposes and their potentials in cancer treatments.