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Khoa Y

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131 “Medicine 3.0” và “5p” trong dự phòng chuyên sâu ung thư vú / Hoàng Thị Ngọc Hà, Hoàng Trung Hiếu, Hà Thị Hiền, Văn Nữ Thùy Linh, Nguyễn Thị Thanh Nhi, Trần Thị Sông Hương, Vũ Vân Anh, Bùi Thị Huyền, Trần Bá Kiên, Ngô Nguyễn Quỳnh Anh, Vincent Nguyễn // Y học cộng đồng (Điện tử) .- 2025 .- Số 1 .- Tr. 45 - 49 .- 610

Dự phòng chuyên sâu ung thư vú đóng vai trò quan trọng trong việc phát hiện sớm, dự phòng và điều trị hiệu quả, giảm tỷ lệ tử vong, nâng cao chất lượng cuộc sống và kéo dài tuổi khoẻ mạnh cho phụ nữ. Theo Globocan 2022, tỷ lệ mắc ung thư vú ở Việt Nam rất cao với xu hướng trẻ hoá, cùng tỷ lệ tử vong cao đáng kể (8,3%). Mục tiêu bài viết này là tổng hợp y văn liên quan đến chăm sóc sức khoẻ chủ động nhằm giúp phụ nữ dự phòng chuyên sâu thư vú. Kết quả: Medicine 3.0 (Y khoa 3.0) là một khái niệm mới, mô tả cách tiếp cận y tế tập trung vào dự phòng và thúc đẩy sức khỏe, thay vì chỉ dừng ở phát hiện sớm và điều trị kịp thời. “5P” trong Medicine 3.0 bao gồm: Prediction (Dự báo), Prevention (Dự phòng), Personalization (Cá thể hoá), Participation (Sự tham gia) và Precision (Sự chính xác), mang lại giải pháp tích hợp hướng đến cộng đồng trong dự phòng chuyên sâu ung thư vú. Vậy nên, Medicine 3.0 khuyến khích phụ nữ chủ động tham gia dự phòng ung thư vú một cách cá thể hoá và chính xác. Kết luận: Cần thúc đẩy ứng dụng Medicine 3.0 và “5P” để nâng cao hiệu quả dự phòng ung thư vú, giảm tỷ lệ tử vong và kéo dài tuổi khoẻ mạnh cho phụ nữ Việt Nam.

132 Kế hoạch MASTER kiểm soát tăng huyết áp của Hiệp hội Tăng huyết áp Châu Âu 2024 / Võ Thị Hà Hoa, Nguyễn Thị Khánh Linh // .- 2025 .- Số 3(70) .- Tr. 159-168 .- 610

Bài báo này nhằm hỗ trợ phổ biến những thông tin quan trọng nhất trong hướng dẫn quản lý bệnh nhân tăng huyết áp, đồng thời thúc đẩy việc áp dụng vào thực hành lâm sàng thông qua việc tóm tắt và phân tích các nội dung chính từ Kế hoạch MASTER 2024.

133 Nghiên cứu thực trạng sâu răng và các yếu tố liên quan của sinh viên năm nhất Đại học Duy Tân năm 2023 / Nguyễn Hoàng Minh Tâm, Nguyễn Thị Huyền Trang, Lê Phạm Quỳnh Như, Lê Đức Anh Tài, Đặng Trịnh Bảo Ngân, Nguyễn Đình Tùng // .- 2025 .- Số 3(70) .- Tr. 169-179 .- 610

Nghiên cứu tìm hiểu thực trạng sâu răng của sinh viên năm thứ nhất và các yếu tố liên quan nhằm mô tả thực trạng sâu răng và tìm hiểu một số yếu tố liên quan đến tình trạng sâu răng ở sinh viên năm nhất Đại học Duy Tân, thành phố Đà Nẵng

134 Prevalence of anxiety and associated factors among women undergoing gynecological surgery: A cross-sectional study / Nguyen Thi Thuy Chung, Nguyen Thi Hong Gam, Nguyen Ngoc Thu , Le Phuong Thanh , Pham Thi Lieu, Nguyen Ba Thiet // .- 2025 .- Tập 190 - Số 5E16 .- P. 205-214 .- 610

This study aimed to evaluate the prevalence and associated factors of anxiety among women scheduled for gynecological surgery. Conducted as a cross-sectional analysis, data collection involved structured interviews that assessed demographics, clinical history, perceptions of postoperative recovery, comprehension of surgical risks, and levels of social support. Anxiety was measured using the GAD-7 scale, and associations between anxiety severity and related factors were examined through ordinal logistic regression. Among the 300 participants, all reported some degree of anxiety, with 60% experiencing mild anxiety, 30% moderate, and 10% severe. Higher anxiety levels were notably linked to limited social support and lower comprehension of counseling. The high prevalence of anxiety observed underscores the need for comprehensive preoperative communication and robust support systems. These strategies could play a vital role in reducing anxiety, ultimately contributing to improved surgical recovery and overall patient well-being.

135 Prevalance of malnutrion and risk of malnutrition and related factors in uncontrolled type 2 diabetic older patients / Nguyen Thi Hoai Thu, Tran Viet Luc, Do Thi Thanh Toan, Vu Thi Thanh Huyen // .- 2025 .- Tập 190 - Số 5E16 .- P. 215-225 .- 613

The aim of this cross-sectional study was to identify the association between nutritional status and related factors among uncontrolled type 2 diabetic older patients. Variables including demographic information, body mass index, frailty, depression, physical activity daily living, comorbidity, polypharmacy and diabetic characteristics. Nutritional status was defined by Mini Nutritional Assessment Short Form. Data was entried by Redcap and analised by Spss 22.0 verson. A total 148 participants with mean of age was 76 ± 7.47 years old, and 62.2% were female.

136 Work motivation and associated factors among health workers in Bac Giang province in 2024: A cross-sectional study / Nguyen Thi Nhan, Nguyen Thi Hoai Thu, Nguyen Hoang Thu Giang, Bui Thi My Anh // .- 2025 .- Tập 190 - Số 5E16 .- P. 226-236 .- 610

Work motivation is crucial for healthcare workers’ performance and the overall effectiveness of the health systems. A well-motivated healthcare workforce can lead to improved patient satisfaction, reduced errors, and a more sustainable health system. This study aimed to describe the work motivation of healthcare workers in Bac Giang province in 2024 and analyze associated factors. A cross-sectional descriptive study was conducted among 253 health workers in Bac Giang province, Viet Yen and Yen Dzung districts using a quantitative approach with structured questionnaire. The main findings revealed that 80.6% of respondents were categorized as having low work motivation, with an average score of 3.66 (SD = 0.37). Significant associations were observed between work motivation and workplace location, years of working in the health field, and night shift frequency.

137 Exploring key determinants of health literacy in type 2 diabetes patients: A cross-sectional study / Do Thi Thu Huyen // .- 2025 .- Tập 190 - Số 5E16 .- P. 237-246 .- 610

Health literacy (HL) is a critical factor in the management of type 2 diabetes mellitus (T2DM), yet many patients lack adequate understanding, leading to poor health outcomes. This study assessed HL among patients with T2DM and identified associated factors. This cross-sectional study involved 358 diabetic outpatients who completed a self-reported questionnaire, including the Health Literacy - Short Form (HL-SF12), Diabetes Self-Management Instruments (DSMI-20), and Multi-Dimensional Support Scale (MDSS).

138 Knowledge of breastfeeding and associated factors in lactating mothers with children below 6 months old in 2023 at E Hospital, Hanoi, Vietnam / Nguyen Thi Thu Uyen, Nguyen Thi Ngoc Anh, Le Thi Thu Phuong, Ninh Thi Phuong Mai, Truong Van Quy // .- 2025 .- Tập 190 - Số 5E16 .- P. 247-257 .- 610

Breastfeeding is a natural and effective way to protect mothers‘ and children‘s health. This research aims to evaluate knowledge of breastfeeding among mothers with their children under 6 months old visiting the E Hospital, a tertiary hospital in Hanoi, Vietnam. A cross-sectional study was conducted using a predesignated, self-administered questionnaire based on the recommendation from the WHO. A special scaling system was employed to calibrate between different types of questions. Data was collected from the survey from 1/2023 to 10/2023 using the platform REDCap and analyzed using the software SPSS®.

139 Delayed diagnosis of Hyperinsulinism Hyperammonemia Syndrome: A case report / Can Thi Bich Ngoc, Nguyen Ngoc Khanh // .- 2025 .- Tập 190 - Số 5E16 .- P. 258-263 .- 610

Hyperinsulinism Hyperammonemia Syndrome (HI/HA syndrome) is an autosomal dominant disease caused by activating mutations in GLUD1, the gene responsible for encoding the mitochondrial enzyme glutamate dehydrogenase (GDH). This syndrome represents the second most common genetic form of congenital hyperinsulinism in infancy. Children with HI/HA syndrome typically experience hypoglycemic symptoms triggered by fasting or high-protein meals and persistently elevated ammonia levels. We report a case of HI/HA syndrome in a 7-month-old female who presented with cyanosis and hyperammonemia, along with an initial normal glucose level at the time of presentation. About one week after the child’s admission to the hospital, we discovered that hypoglycemia was the cause of her irritability. The hypoglycemic episode was found to occur coincidentally with hyperammonemia. The combination of clinical findings, biochemical markers, and genetic sequencing identifying a GLUD1 pathogenic variant facilitated the correct diagnosis of HI/HA syndrome. As demonstrated by this case, the diagnosis of HI/HA syndrome requires a thorough clinical evaluation, comprehensive biochemical analysis, and genetic testing. With the correct diagnosis, a patient with HI/HA syndrome can receive ongoing monitoring and care with the goal of preventing adverse neurologic sequelae.

140 Kenny-Caffey Syndrome type 2: Insight from two Vietnamese cases / Can Thi Bich Ngoc, Nguyen Ngoc Khanh // .- 2025 .- Tập 190 - Số 5E16 .- P. 264-270 .- 610

We report two unrelated 8-year-old Vietnamese girls diagnosed with Kenny-Caffey Syndrome type 2 (KCS2), each harboring the same heterozygous pathogenic variant in the FAM111A gene (c.1706G>A, p.Arg569His). Case 1 presented initially at age 4 with poor growth and persistent anterior fontanelle. At age 8, she exhibited severe short stature (-4.5 SDS), macrocephaly, small hands, and craniofacial dysmorphisms. Additional findings included persistent fontanelle, hyperopia with amblyopia, cortical thickening of long bones, and asymptomatic hypocalcemia with normal parathyroid hormone (PTH) levels. Brain MRI showed a thin pituitary gland. Case 2 presented with short stature (-4.96 SDS), a history of hypocalcemic seizures, and congenital astigmatism. She had normal facial appearance but showed cortical bone thinning, absent pituitary lobes, and hypocalcemia with inappropriately low PTH levels. Despite calcium supplementation, normocalcemia was achieved only after calcitriol therapy. Growth hormone was later initiated with favorable growth response. Both cases underscore the variable expressivity of KCS2 and highlight the diagnostic value of genetic testing in children with unexplained short stature, skeletal anomalies, and calcium disturbances. The study contributed additional data on NKX6-2 variants in Vietnamese patients.