CSDL Bài trích Báo - Tạp chí
Khoa Dược
11 Nghiên cứu bào chế và đánh giá chất lượng viên nang cứng chứa cao chiết nụ Hòe (Flos Sophorae Immaturus) / Huỳnh Lời, Phạm Thị Hồng Khuyên, Dương Thị Thuấn // .- 2025 .- Số 3(70) .- Tr. 52-62 .- 615
Khảo sát thành phần viên nang cứng với lượng cao chiết và tá dược bao gồm cao chiết nụ Hòe 153 mg, lactose monohydrat 276 mg, PVP K30 3,4 mg, aerosil 2 mg. Đánh giá chất lượng viên nang dựa vào các tiêu chuẩn của DĐVN V bao gồm cảm quan, định tính, độ đồng đều, độ hòa tan và định lượng.
12 Khảo sát thay đổi hàm lượng flavonoid và hoạt tính chống oxy hóa của dược liệu Ngải cứu chế biến chích rượu, chích giấm và thán sao / Đoàn Thị Ái Nghĩa, Lê Thị Bảo Yến, Phạm Thị Hiền Thư, Trần Xuân Phú, Nguyễn Thị Ngọc Kiều, Trần Thị Khánh Huyền // .- 2025 .- Số 3(70) .- Tr. 63-68 .- 615
Xác định sự thay đổi định tính thành phần hóa học, hàm lượng flavonoid và hoạt tính chống oxy hóa của vị thuốc Ngải cứu chế biến so với dược liệu ban đầu. Định lượng flavonoid toàn phần bằng thuốc thử AlCl3. Đánh giá tác dụng chống oxy hóa bằng phương pháp trung hòa gốc tự do DPPH.
13 Effects of FU Plus tablets on intracavernosal pressure in animal experimentsanimals / Pham Thi Van Anh, Do Dieu Linh, Dau Thuy Duong // .- 2025 .- Tập 190 - Số 5E16 .- P. 130-136 .- 615
Erectile dysfunction is defined as the persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance, that may affect physical and psychosocial health, and the patients quality of life. A popular trend is to discover and research therapeutic drugs derived from medicinal herbs. FU Plus tablets including Epimedium extract, Tribulus Terrestris Extract, L-Arginine HCl, Red Ginseng extract, Zinc gluconate, Selenium yeast and Yohimbine HCl is a product expected to treat erectile dysfunction. The study was carried out to evaluate the effects of FU Plus tablets on the erectile function through intracavernosal pressure (ICP) in experimental animals. Wistar rats were divided into 3 groups of ten that were given normal saline, sildenafil and FU Plus tablets, respectively. ICP response after cavernous nerve stimulation was recorded. Sildenafil-treated rats and FU Plus-treated rats had shorter response latency, higher peak ICP and longer response duration than untreated control rats. In conclusion, FU Plus tablets have the potential for treating erectile dysfunction.
14 In vivo assessment of acute and subchronic toxicity of Nanochitin in experimental animals / Nguyen Thi Cha, Ho Phu Ha, Nguyen Tien Thanh, Bui Tien Hung, Pham Thi Van Anh, Nguyen Thi Thanh Ha, Trinh Vinh Quang, Dinh Thi Thu Hang // .- 2025 .- Tập 190 - Số 5E16 .- P. 137-144 .- 615
This study aimed to evaluate the safety of Nanochitin through oral administration in experimental animals. The acute toxicity was determined in mice at ascending doses and the subchronic toxicity was evaluated in rats with oral doses of 15.6 mg/kg b.w/day and 46.8 mg/kg b.w/day for 30 days.
15 Experimental evaluation of the subchronic toxicity of Phong Te Thap Ba Giang / Pham Thi Van Anh, Bui Tien Hung, Vu Xuan Hai, Nguyen Thi Ha, Dau Thuy Duong // .- 2025 .- Tập 190 - Số 5E16 .- P. 145-152 .- 610
Musculoskeletal disorders have become a global health burden. Phong Te Thap Ba Giang is a traditional medicine that has been used for a long time to treat various musculoskeletal disorders. This study was conducted to evaluate the subchronic toxicity of Phong te thap Ba Giang in experimental animals.
16 An experimental study on the skin irritant potential of Dinh Tho patch / Dam Thi Tu Anh, Pham Thi Van Anh, Do Thi Minh Phuong, Hoang My Hanh, Le Hai Trung, Dau Thuy Duong // .- 2025 .- Tập 190 - Số 5E16 .- P. 153-158 .- 615
Dinh Tho patches are the transdermal combination of medicinal herbs including Dracaena cambodiana Pierre ex Gagnep, Cinnamomum cassia, Kaempferia galanga, Homalomena occulta, Caesalpinia sappan, Illicium verum, Artemisia vulgaris and Reynoutria japonica with the intended indication to treat symptoms of swelling, bruising, tension and pain of the musculoskeletal system. This study was carried out to examine the skin irritation of Dinh Tho patches in experimental animals.
17 A 90-day toxicological assessment of KRG hard capsules containing a water extract of Korean red ginseng in Wistar rats / Yang Deok-Chun, Pham Thi Van Anh, Cho Young Mi, Kwon Jeong Eun, Nguyen Thi Thuy, Kang Se Chan, Kong Byoung Man, Choi Sung Keun, Hoang Van An, Doan Ha Thang, Bui Thi Huong Thao, Dinh Thi Thu Hang, Dang Thi Ngoc Mai, Dang Thi Thu Hien, Mai Phuong Thanh // .- 2025 .- Tập 190 - Số 5E16 .- P. 159-168 .- 615
The KRG hard capsule was produced by Daedong Korea Ginseng Co. Ltd., with Korean red ginseng (Panax ginseng C. A. Meyer) as its primary component. This study aimed to assess the toxicity of KRG following 90 days of repeated oral dosing. Male and female Wistar rats received the test capsule orally once daily at 120 and 360 mg/kg/day over 90 days. The Korean red ginseng extract administration did not lead to any significant toxicological effects regarding mortality, body weight, hematological parameters, serum biochemistry, gross pathological observations, or histopathological analysis. Consequently, based on this toxicological evaluation, the KRG hard capsules are considered safe and non-toxic. The findings may serve as adequate preclinical evidence to support the initiation of future clinical trials involving KRG.
18 Evaluating the acute toxicity and hepatoprotective effect of PROTECFUL hard capsule on paracetamol-induced acute hepatitis in mice / Tran Thanh Tung, La Que Lam, Nguyen Thi Thanh Loan // .- 2025 .- Tập 190 - Số 5E16 .- P. 169-178 .- 615
Drug-induced liver injury is characterized by liver damage due to pharmaceutical compounds, resulting in a wide range of liver disorders, from asymptomatic elevations in liver enzymes to full liver failure. It is a leading cause of acute liver failure in many countries. This study investigated the acute toxicity and evaluated hepatoprotective effects on paracetamol-induced acute hepatitis of PROTECFUL hard capsules in Swiss mice. The acute toxicity was assessed through oral administration, and a fifty percent lethal dose was determined using the Litchfield-Wilcoxon method.
19 In vitro xanthine oxidase inhibitory and in vivo hypouricemic activity of dual herbal combination comprising Carica papaya L. and Piper lolot C. DC leaves / Phan Hong Minh, Ho My Dung, Le Anh Tuan , Nguyen Thuc Thu Huong, Tran Thi Hong Ngoc, Nguyen Thi Thu Hien, Mai Phuong Thanh // .- 2025 .- Tập 190 - Số 5E16 .- P. 179-187 .- 615
Hyperuricemia has emerged as a major public health issue in recent years, with existing treatments often associated with negative side effects for patients. This research examined the anti-hyperuricemic properties of a dual herbal extract made from Carica papaya L. and Piper lolot C.DC leaves, utilizing a xanthine oxidase inhibitory assay and a hyperuricemic mouse model induced by potassium oxonate (500 mg/kg body weight).
20 Anti-inflammatory effects of the extracts from Ardisia silvestris Pitard leaves in experiment / Mai Phuong Thanh, Ho My Dung, Le Anh Tuan, Nguyen Thuc Thu Huong, Tran Thi Hong Ngoc, Le Thi Le Giang, Phan Hong Minh // .- 2025 .- Tập 190 - Số 5E16 .- P. 188-195 .- 615
This research aimed to explore the anti-inflammatory effects of n-hexane, ethyl acetate (EtOAc), and n-butanol extracts from the leaves of Ardisia silvestris Pitard, both in vitro and in vivo, specifically focusing on the EtOAc extract. The in vitro assessment of anti-inflammatory activity involved measuring the inhibition of nitric oxide (NO) production in LPS-stimulated RAW 264.7 macrophage cells. The findings revealed that the EtOAc extract exhibited the highest potency, with an IC50 value of 52.10 ± 2.07 µg/mL, effectively inhibiting NO production without causing cellular damage. In vivo, the EtOAc extract’s anti-inflammatory properties were evaluated using carrageenan-induced paw edema in rats and the cotton pellet-induced granuloma test in mice. At both tested dosages, the EtOAc extract significantly reduced paw edema induced by carrageenan in rats. Additionally, it effectively inhibited exudate and granuloma formation following cotton pellet implantation at both doses, indicating its anti-inflammatory activity during the subacute phase of inflammation. Overall, these results strongly suggest that the ethyl acetate extract of Ardisia silvestris Pitard possesses significant anti-inflammatory properties and may be beneficial in traditionally treating various inflammatory conditions.