Screening and characterization of paclitaxel-producing fungus Talaromyces wortmannii WQF18 isolated from Cephalotaxus mannii Hook.f.
Tác giả: Quach Ngoc Tung, Vu Thi Hanh Nguyen, Pham Quynh Anh, Tran Hong Quang, Chu Hoang Ha, Phi Quyet Tien
Số trang:
P. 77-85
Số phát hành:
Volume 45 - Number 1 - March 3
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
615
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Academia Journal of Biology, Sinh học
Chủ đề:
Dược học
Tóm tắt:
Cephalotaxus mannii Hook. f. is a rare evergreen conifer native listed in the International Union for Conservation of Nature (IUCN) Red List, which is utilized for leukemia treatment. Although endophytic fungi from C. mannii was reported before, their cytotoxic property has not been revealed yet. In the present study, a total of 7 endophytic fungi were isolated from C. mannii collected in Ha Giang province, Vietnam, among which the isolate WQF18 was active against 5 tested pathogens with inhibition zones ranging from 18.0 ± 0.7 to 25.0 ± 0.4 mm.
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