CSDL Bài trích Báo - Tạp chí
Evaluation of antitumor activity of saphia alkali K90 on dmba-induced carcinogenesis in swiss mice
Tác giả: Pham Thi Van Anh, Nguyen Phuong Dung, Mai Phuong Thanh
Số trang:
P. 106-114
Số phát hành:
Volume 177 E14 - N 04 - May
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Saphia Alkali K90, tumor, DMBA, mice
Chủ đề:
Cancer cells
Tóm tắt:
The present study aimed to initially evaluate the anti-tumor effect of orally administered Saphia Alkali K90 in 7,12-dimethylbenz(a)anthracene (DMBA)-induced carcinogenesis in Swiss mice. Mice exposed to DMBA (total dose of 6 mg, p.o.) were treated with SAK90 at 15 ml/kg BW and 45 ml/kg BW daily. The vehicle was given to both normal and diseased controls. The change in body weight, mortality rate, tumor incidence, tumor burden, tumor yield, histopathology, and hematological and biochemical parameters were evaluated after 16 weeks of treatment.
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