Serum vascular endothelial growth factor levels and some characteristics of diabetic retinopathy patients
Tác giả: Vu Van Nga, Nguyen Thi Binh Minh, Dinh Thi My Dung, Nguyen Thi Lan Anh, Hoang Thi Thu Ha, Le Thi Minh Phuong, Do Thi Le Hang, Do Thi Quynh, Pham Thi Thuy An, Le Ngoc Thanh, Tran Van Khanh, Vu Thi ThomTóm tắt:
Diabetic retinopathy (DR) is a dangerous microvascular complication of diabetes mellitus (DM). The escalating prevalence of diabetes increases the rate of DR patients in Vietnam. Numerous studies have indicated that serum vascular endothelial growth factor (VEGF) can be used as a marker for monitoring the progression of this disease. Our study included 150 diabetic patients and 75 healthy individuals in the control group. Our study included 150 diabetic patients and a control group of 75 healthy individuals. We investigated the association between serum VEGF levels and some characteristics in diabetic retinopathy patients. Clinical data (pulse, blood pressure, medical history, and body mass index) and paraclinical data (Glucose, HbA1c) were collected. Serum samples were analyzed to determine VEGF concentrations. Our study fond that serum VEGF levels were higher in the group with DR compared to the other two groups and exhibited a correlation with glucose levels in diabetic patients (p < 0.05).
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