Resistome and plasmidome in an extensively drug-resistant extra-intestinal pathogenic Escherichia coli isolated from a one-year-old child with respiratory distress syndrome
Tác giả: Nguyen Van Anh, Nguyen Thuy Duong, Tran Thi Thanh Tam, Nguyen Quang Huy
Số trang:
P. 305-316
Số phát hành:
Vol 21 - Number 2
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
618.92 22
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Extra-intestinal pathogenic Escherichia coli (ExPEC), resistome, plasmidome, extensively drug resistance, carbapenem resistance, whole-genome sequencing
Chủ đề:
Pediatrics
Tóm tắt:
This study aimed at identifying resistome and plasmidomes carrying antibiotic-resistant genes (ARGs) in an extensively drug-resistant extra-intestinal pathogenic E. coli strain XP817 isolated from a one-year-old child with respiratory distress syndrome. Whole genome analysis of strain XP817 revealed 68 ARGs documented in the Comprehensive Antibiotic Resistance Database (CARD). In conclusion, our study underlines the crucial role of the ARG dissemination via horizontal gene transfer in E. coli as well as in the Enterobacteriaceae family.