CSDL Bài trích Báo - Tạp chí
chủ đề: Pediatrics
1 IgG4-related disease: A systematic review of a rare pediatric condition / Mai Thanh Cong, Hoang Mai Phuong, Dao Khanh Ly // .- 2024 .- Volume 184 E15 - N 11 .- P. 24-41 .- 610
Immunoglobulin G4 related disease (IgG4-RD) is an immune-mediated fibroinflammatory disorder, marked by tumor-like mass-forming lesions. IgG4-RD is a recently recognized condition and has a few conducted research on the pediatric population. This study aims to provide some insights into the epidemiology, histological findings, diagnosis, and treatment of this condition in children. A systematic literature search was performed on Embase, PubMed, and Web-of-science for case reports and case series of IgG4-RD in children published between 1/2015 and 12/2023. 58 case reports and case series including 62 cases of IgG4-RD in children were identified. The mean age was 12 ± 4.4 years old, of which 54.8% were male. The orbit and central nervous system were two organs predominantly affected. Multi-organ involvement was reported in 14 cases (22.6%). Of 53 patients with serum IgG4 concentration reported, 60.4% of them had elevated serum IgG4 level. 21 patients (33.8%) had fulfilled the definitive diagnosis of the 2020 revised comprehensive diagnostic criteria. Prednisone was the first choice of treatment in 81.8% of the cases. 77.6% of the patients were treated with steroid-sparing DMARDs.
2 Resistome and plasmidome in an extensively drug-resistant extra-intestinal pathogenic Escherichia coli isolated from a one-year-old child with respiratory distress syndrome / Nguyen Van Anh, Nguyen Thuy Duong, Tran Thi Thanh Tam, Nguyen Quang Huy // .- 2023 .- Vol 21 - Number 2 .- P. 305-316 .- 618.92 22
This study aimed at identifying resistome and plasmidomes carrying antibiotic-resistant genes (ARGs) in an extensively drug-resistant extra-intestinal pathogenic E. coli strain XP817 isolated from a one-year-old child with respiratory distress syndrome. Whole genome analysis of strain XP817 revealed 68 ARGs documented in the Comprehensive Antibiotic Resistance Database (CARD). In conclusion, our study underlines the crucial role of the ARG dissemination via horizontal gene transfer in E. coli as well as in the Enterobacteriaceae family.