CSDL Bài trích Báo - Tạp chí
Expression of transcription factors involved in epithelial-to-mesenchymal transition of the breast cancer cell line MCF-7 co-cultured with adipose tissue mesenchymal stem cells
Tác giả: Vu Thi Tien, Le Hoang Duc, Bui Van Ngoc, Nguyen Trung Nam
Số trang:
P. 249-257
Số phát hành:
Vol 21 - Number 2
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Gene expression, epithelial-to-mesenchymal transformation, co-culture, breast cancer, mesenchymal stem cells
Chủ đề:
Breast cancer
Tóm tắt:
Breast cancer is the most frequently diagnosed cancer in women globally. The tumor microenvironment plays a vital role in epithelial-to-mesenchymal transition (EMT), leading to the invasion and metastasis of cancer cells. The tumor microenvironment includes all components of the tumor cells, including the extracellular matrix, tumor vasculature, mesenchymal stem cells, immune cells, and fibroblasts. Understanding the interactions between mesenchymal stem cells and cancer cells is essential in determining the role of mesenchymal stem cells in diagnosing and treating breast cancer.