Identification of hub genes and drug-gene interactions for targeted breast cancer treatment by integrated bioinformatics analysis
Tác giả: Dao Manh Cuong, Bui Van Ngoc
Số trang:
P. 21-34
Số phát hành:
Vol 21 - Number 1
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Biomarker, breast cancer, drug-gene interaction, hub gene, protein-protein interaction
Chủ đề:
Breast cancer
Tóm tắt:
In this study, bioinformatics is applied to genetic testing for BC diagnosis; namely the R programming language combined with the bioinformatics toolkit was used to analyze gene expression levels between normal and tumor tissues in three gene expression profiles (GSE29431, GSE42568, GSE21422).
Tạp chí liên quan
- Identification of the potential compounds for inhibition CD44 target of human breast cancer stem cells by docking method
- A nonsense mutation in BRCA1 gene in a Vietnamese patient with breast cancer
- Expression of transcription factors involved in epithelial-to-mesenchymal transition of the breast cancer cell line MCF-7 co-cultured with adipose tissue mesenchymal stem cells