Tóm tắt:

Many studies show that hyperglycemia can lead to injury to the intestinal mucosal barrier, increasing the likelihood of infection, leading to intestinal inflammation in people with type 2 diabetes. Recently, investigations indicatethat the gut microbiome plays a very important role in thisdiseaseinwhichLactobacillus in the guthas been shown to regulate glucose and lipid metabolism, improving oxidative stress, andinhibiting inflammatory responses. In this study, by the method of oriented isolation,the number of Lactobacillus bacteria in the subgroup of healthy people was determined to be (3,9 ± 1.2) x 103CFU/g and in the group of diabetic patients was (2.7 ± 0.8) x 103 CFU/g. The study identified 17/68 selected Lactobacillus strains that were resistant to both Staphylococcus aureusATCC13709 and Escherichia coliATCC 11105. Moreover, these strains were also resistant to acid pH 2.