The association of CFAP65 with male infertility in Vietnamese individuals
Tác giả: Nguyen Thuy Duong, Tran Huu Dinh, Nong Van Hai
Số trang:
P. 09-14
Tên tạp chí:
Công nghệ sinh học - Vietnam Journal of Biotechnology
Số phát hành:
Vol 20 - N1
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
CFAP65, rs117885048, Vietnam, PCR-RFLP, male infertility
Chủ đề:
Pathology
Tóm tắt:
The study aimed to investigate the correlation between the polymorphism CFAP65 rs117885048 and male infertility in a Vietnamese population comprising 207 infertile men and 217 healthy controls. As a result, the studied population followed Hardy-Weinberg equilibrium (HWE) (p> 0.05) and the frequencies of genotypes CC/CT/TT were 0.875, 0.12, and 0.003, respectively. The Chi-square test revealed no association between the polymorphism CFAP65 rs117885048 and the disease in this population (p > 0.05). To further interpret the correlation between single nucleotide polymorphisms in the CFAP65 gene and male infertility, a more comprehensive study with other polymorphisms needs to be considered.
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