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The association of CFAP65 with male infertility in Vietnamese individuals

Tác giả: Nguyen Thuy Duong, Tran Huu Dinh, Nong Van Hai
Số trang: P. 09-14
Tên tạp chí: Công nghệ sinh học - Vietnam Journal of Biotechnology
Số phát hành: Vol 20 - N1
Kiểu tài liệu: Tạp chí trong nước
Nơi lưu trữ: 03 Quang Trung
Mã phân loại: 610
Ngôn ngữ: Tiếng Anh
Từ khóa: CFAP65, rs117885048, Vietnam, PCR-RFLP, male infertility
Chủ đề: Pathology
Tóm tắt:

The study aimed to investigate the correlation between the polymorphism CFAP65 rs117885048 and male infertility in a Vietnamese population comprising 207 infertile men and 217 healthy controls. As a result, the studied population followed Hardy-Weinberg equilibrium (HWE) (p> 0.05) and the frequencies of genotypes CC/CT/TT were 0.875, 0.12, and 0.003, respectively. The Chi-square test revealed no association between the polymorphism CFAP65 rs117885048 and the disease in this population (p > 0.05). To further interpret the correlation between single nucleotide polymorphisms in the CFAP65 gene and male infertility, a more comprehensive study with other polymorphisms needs to be considered.

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