This study compared results of online circular contrast perimetry (OCCP) versus standard automated perimetry (SAP) in clinic, as well as clinic OCCP versus home OCCP in a normal Asian population. Healthy participants underwent a comprehensive ocular examination, retinal nerve fiber layer optical coherence tomography scan, and visual field tests performed in clinic, using OCCP and SAP. Within a week, participants were asked to repeat OCCP field test at home. 58 eyes of 29 healthy volunteers were selected. At the clinic, no difference between testing duration and fixation loss of SAP and OCCP was detected.
A retrospective study of 61 patients was conducted to evaluate the preliminary results of maximal cytoreductive surgery following neoadjuvant chemotherapy for FIGO stage IIIC-IV ovarian cancer from 2019 to 2023.
This study aims to evaluate the value of the platelet-to-albumin ratio (PAR) in predicting acute kidney injury (AKI) in patients with decompensated cirrhosis. A descriptive cross-sectional analysis was conducted at multiple centers on 295 patients with decompensated cirrhosis, treated at the Department of Gastroenterology - Can Tho Central General Hospital and the Department of Gastroenterology - Bac Lieu General Hospital from June 2019 to May 2021.
Air pollution is a significant global health concern, linked to numerous severe health outcomes, particularly respiratory infections. However, the effects of air pollution components on upper respiratory tract infections (URTI) remain limited. This study aims to synthesize the impact of air pollution on URTI from 2010 to 2019 to provide a basis for effective public health interventions.
Immune-related pneumonitis is a rare but serious complication in patients with non-small cell lung cancer (NSCLC) treated with durvalumab after concurrent chemoradiotherapy (CRT). We encountered a 61-year-old male with stage III non-small cell lung cancer (NSCLC) receiving concurrent chemoradiotherapy followed by durvalumab maintenance therapy. After 1 cycle of durvalumab treatment, he developed progressive dyspnea, dry cough, and low-grade fever. Chest CT scans revealed diffuse ground-glass opacities in both lungs, indicative of immune-related pneumonitis. Durvalumab was discontinued, and the patient was treated with high-dose corticosteroids and antibiotics. After one month, he fully recovered. Durvalumab was cautiously resumed under close monitoring without recurrence of pneumonitis. Conclusion: Early identification and management of immune-related pneumonitis are essential in NSCLC patients receiving durvalumab. Reintroducing durvalumab after recovery may be safe with vigilant monitoring.
The expanded NIPT for screening all fetal chromosomal aneuploidies has been widely used in clinical practice. The study was conducted on 6,104 pregnant women performing this test at Medlatec General Hospital to evaluate the values of NIPT.
To evaluate the value of apolipoprotein A-I, B, and the apoB/AI ratio in the diagnostic of peripheral artery disease among patients with diabetes, we conducted a cross-sectional study of which they underwent clinical evaluation, standardized Doppler ultrasound and blood test. Area under the Receiver Operating Characteristic curve method was employed to estimate the discriminatory ability of apolipoprotein A-I, apolipoprotein B, and the ApoB/A-I ratio. A total of 159 patients were included. ApoA-I, ApoB, and the ApoB/A-I ratio show statistically significant associations with most clinical and Doppler ultrasound characteristics of PAD. In Pearson’s correlation analysis, apolipoproteins showed a stronger correlation with ABI than the traditional lipid profile.
Gastric cancer ranked fourth for incidence and mortality of all cancers in Vietnam. Clinical symptoms in the early stages are often nonspecific. Patients may have epigastric pain, anorexia or weight loss. Gastroscopy combined with biopsy is a clinical test that helps diagnose gastric cancer. Endoscopic ultrasound, computed tomography of the abdomen and chest are important examinations to assess the stage of the disease. Gastric cancer patients had a high rate of malnutrition, and preoperative nutritional management represents a challenge. Cross-sectional descriptive research was conducted on 88 gastric cancer patients aged over 18 years old to describe preoperative clinical, subclinical characteristics and nutritional status at National Cancer Hospital from January to December 2023.
Phuong Dong Dai Trang tablet is a mixture of medicinal herbs including Hedychium coronarium, Coix lacryma-jobi, Dioscorea persimilis, Cynara Scolymus L., Paeonia lactiflora, and Glochidion eriocarpum. This study was carried out to evaluate the protective and curative effects of Phuong Dong Dai Trang tablets on mustard oil-induced irritable bowel syndrome model in mice. Swiss mice were divided into six groups that were given orally 0.9% sodium chloride (group 1 - 3), Duspatalin (mebeverine) 80 mg/kg b.w./day (group 4), Phuong Dong Dai Trang tablets 1080 mg/kg b.w./day (group 5) and Phuong Dong Dai Trang tablets 3240 mg/kg/b.w./day (group 6). Mice of group 3 - 6 were induced diarrhea-predominant irritable bowel syndrome by mustard oil colonic administration before or after oral treatment. The research indices included the intestinal motility measured by charcoal meal test, colon macroscopic and microscopic scores. Our findings showed that Phuong Dong Dai Trang tablets at 3240 mg/kg b.w./day reduced the intestinal motility and the stool score significantly in mice. Phuong Dong Dai Trang tablets at 1080 mg/kg b.w./day improved the stool score and tended to decrease the intestinal motility in mice.
Academic pressure, stress, and associated factors are pervasive throughout education. Lately, depression, anxiety, and stress emerged as alarming mental health issues among health science students. A cross-sectional descriptive study was conducted among 2,064 students at Can Tho Medical College to determine the prevalence of depression, anxiety, and stress, along with associated factors. Data were collected online using the DASS-21 questionnaire via Google Forms. The prevalence rates of depression, anxiety, and stress among college students were 52.4%, 73.1%, and 58.8%, respectively. Factors associated with these conditions included gender, body satisfaction, daily smartphone use, primary smartphone activities, satisfaction with academic performance, ease of forming friendships, and presence of close friends. As depression, anxiety, and stress were significant concerns among medical college students, educators should implement screening programs and develop strategies to improve and enhance students’ mental health.
