Bài viết hệ thống hóa cơ sở lý luận về lãnh đạo và phong cách lãnh đạo của đội ngũ lãnh đạo chủ chốt tại các doanh nghiệp nhà nước, phân tích kinh nghiệm quốc tế về nghiên cứu phong cách lãnh đạo làm cơ sở cho việc nhận thức và hình thành phong cách lãnh đạo của đội ngũ lãnh đạo chủ chốt tại các doanh nghiệp nhà nước trong bối cảnh mới.
Hợp tác y tế giữa 2 quốc gia được hình thành kể từ khi 2 nước ký kết Hiệp định hợp tác trong lĩnh vực y tế năm 1984. Bằng việc phân tích các nguồn tài liệu có liên quan, nghiên cứu hướng đến việc đánh giá về thực trạng hợp tác y tế giữa 2 quốc gia trên các lĩnh vực như: trao đổi chuyên gia, hỗ trợ trang thiết bị y tế và hợp tác trong công tác phòng, chống dịch bệnh, qua đó rút ra bài học kinh nghiệm về tiềm năng hợp tác giữa Việt Nam và Angola trong tương lai.
Carbofuran is frequently applied to crop fields to combat insects globally causing serious environmental pollution. In this study, the enhanced degradation of carbofuran in soil by augmentation with Bacillus sp. DT1 was determined. The results showed that the augmentation with the bacterial strain increased the degradation by almost 30% compared to attenuation after 30 days at an initial concentration of 10 mg/kg dry soil. The half-life values of the insecticide were 41.6 and 17.9 days for attenuation and augmentation, respectively. Moreover, the augmentation with Bacillus sp. DT1 significantly increased sequence numbers of 16 S rRNA in soil compared to the initial stage. However, α-diversity indices, i.e., values of OTUs, ACE, Chao1 and Shannon showed no statistical differences in soil with and without the insecticide addition, with and without augmentation after 30 days. These results showed that carbofuran did not inhibit or stimulate the growth of soil bacteria at 10 mg/kg dry soil.
In this study, we analyzed the mitochondrial DNA sequences taken from 120 males belonging Hmong-Mien (HM) language family in Vietnam: Dao, Hmong, and Pathen, revealing 352 unique variants. Dao has the most number of polymorphisms (230 unique SNPs occurring 1469 times), followed by Hmong (181 unique SNPs occurring 1367 times) and Pathen (159 SNPs occurring 1243 times). Genetic variations within each population and among Hmong-Mien speakers were further measured by computations of haplotype diversity (H), nucleotide diversity (π) and fixation index (FST).
The hot-spots of transmission of food-borne zoonotic trematodes in northern Vietnam have been known as the integrated fish-livestock (VAC- Garden, Fish pond, Poultry shed) ponds. A cross-sectional study was conducted in Ha Noi capital and Yen Bai province to investigate the trematode larval infections (cercariae) in freshwater snails in these areas. Snails were collected from 35 VAC ponds, including 25 grow-out and 10 nursery ponds. A total of 13,895 specimens of 12 snail species were examined for cercariae shedding. Six of 12 snail species including Melanoides tuberculata, Tarebia granifera, Radix auriculata, Gyraulus convexiusculus, Bithynia fuchsiana and Parafosarulus manchouricus, shed cercariae. Seven cercarial types were detected. The amount of snails and the prevalent infection in nursery ponds were 1.14 and 1.3 times higher than in grow-out ponds, respectively. Thus, VAC ponds in northern Vietnam are still the hot-spot for trematode larval infection.
In this study, whole-exome sequencing was performed to screen mutations in the AR gene as well as genes related to disorders of sex development (DSD). Sanger sequencing was applied to validate the mutations in the patient. One missense mutation in the AR gene which was reported previously was identified in the patient. In this site, nucleotide G is changed to A at position 2194 on cDNA (c.G2194A), leading to a substitution of aspartic at position 732 aspartic to asparagine (p.Asp732Asn). However, this is the first published case in a Vietnamese with this mutation. Our study expands the mutation spectrum of the AR gene in Vietnamese patients and confirms the usefulness of whole-exome sequencing in the diagnosis of AIS. The results of the study are the basis for supporting doctors in prenatal diagnosis and giving reasonable advice to patients and families.
Male infertility is a reproductive disease caused by various factors, including environmental factors and genetic defects. Thousands of genes have been identified to cause and associate with male infertility, such as TEX15. Our study aimed to identify the association between the polymorphism TEX15 rs142485241 and male infertility. Total DNAs were extracted from the whole blood of 429 unrelated Vietnamese individuals, including 202 healthy controls and 227 patients with male infertility. The genotypes and alleles of the polymorphism were determined by the PCR-RFLP method. The data were analyzed by statistical methods to assess the association of TEX15 rs142485241 with male infertility. The results showed that the distribution of genotypes of the polymorphism followed the Hardy-Weinberg equilibrium (p-value > 0.05). However, no association was established between the polymorphism TEX15 rs142485241 and male infertility in the three models (additive, dominant, and recessive) (p-value > 0.05). This study would contribute to the knowledge about the association of TEX15 with male infertility in the Vietnamese population.
To characterize the cellular stress by n-alkanols with different alkyl chain lengths in Escherichia coli, we investigated how n-alkanols damage cell envelope permeability and whether they enhance the promoter activity of the envelope stress response regulator, σE, by using variants of green fluorescent protein (GFP). By using E. coli cells having GFPuv expressing and localizing in the cytoplasm, the inner membrane, and the periplasm, after exposure to n-alkanols, the fluorescent intensity of GFPuv released from cells was examined. Our data showed that at the similar levels of cell death of about 90–97%, ethanol, a short-chain alkanol, at a concentration of 20% damaged the outer membrane more greatly than the inner membrane, whereas a longer-chain alkanol of pentanol at a concentration of 1.125% damaged both of the outer and inner membranes. Then we investigated the envelope stress response to n-alkanols by σE factor by ratiometric analysis of rpoE promoter activity for the downstream GFPuv expression referenced to that of housekeeping sigma 70 (σ70 ) recognizing lacUV5 promoter for red fluorescent protein (RFP) expression. The results indicated that the relative activity of rpoE promoter by pentanol was much greater than that of ethanol. The degree of its sensitization by rpoE deficiency was much more remarkable for cells treated with pentanol than for those with ethanol. The results suggest that the response of the σE plays a significant role in the membrane integrity and survival of E. coli cells treated with n-alkanols depending on the alkyl chain length of the molecule.
This study aimed to assess the effects of simulated microgravity (SMG) on senescent human fibroblasts (HFs). The HFs were treated with 150 µM H2O2 in a culture medium for 90 minutes for senescent induction. The senescent HFs were induced SMG for 72 hours by a Gravity simulator, while the control group was treated in the same CO2 incubator. Cell morphology analysis showed that the SMG condition retrieved the fibroblastic morphology from the senescence. WST1 assay and cell counting indicated that the senescent HFs viability from the SMG group was higher than the control group (OD value of 0.80 ± 0.13 vs. 0.64 ± 0.11, respectively).
Trình bày những kết quả nổi bật về khuôn khổ pháp lý tổ chức và quản lý hoạt động thị trường chứng khoán Việt Nam. Một số nội dung cần tiếp tục hoàn khuôn khổ pháp luật thị trường chứng khoán Việt Nam và các khuyến nghị.
