CSDL Bài trích Báo - Tạp chí
Neoadjuvant chemotherapy with FLOT for locally advanced gastric cancer: A single-center experience from Vietnam
Tác giả: Dinh Thi Hai Duyen, Vu Van Tien, Nguyen Thi Mai Lan
Số trang:
P. 41-51
Số phát hành:
Tập 190 - Số 5E16
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
FLOT, neoadjuvant chemotherapy, gastric cancer, R0 resection, locally advanced cancer, Vietnam
Chủ đề:
Gastric cancer--Ung thư dạ dày
Tóm tắt:
Neoadjuvant chemotherapy (NACT) with the FLOT regimen (5-Fluorouracil, Leucovorin, Oxaliplatin, Docetaxel) has shown promising results for locally advanced gastric cancer (LAGC). This study aimed to evaluate the initial treatment outcomes of LAGC patients receiving neoadjuvant FLOT at Hanoi Oncology Hospital. A descriptive cohort study was conducted on 35 patients with LAGC (cT3-4 and/or cN2-3, M0) treated with neoadjuvant FLOT between October 2021 and February 2024. Clinical data, radiological and histopathological responses, surgical outcomes, and adverse events were retrospectively and prospectively collected and analyzed.