Tóm tắt:

Chronic obstructive pulmonary disease (COPD) is a common disease which negatively affects living quality and longevity of patients. In this study, we evaluated plasma IL-1β and IL-8 concentrations in 10 stage-D COPD patients before being transplanted with allogeneic MSCs derived from umbilical cord tissues (UC-MSCs) activated by platelet-rich plasma (PRP) and at 4 follow- ups (after 1, 3, 7, 12 months), as well as determined their associations with COPD clinical and sub-clinical parameters.