CSDL Bài trích Báo - Tạp chí
Effects of simulated microgravity on senescent human fibroblasts
Tác giả: Ly Ngoc Cang, Hoang Nghia Quang Huy, Hoang Nghia Son, Le Thanh Long
Số trang:
P. 115-122
Tên tạp chí:
Academia Journal of Biology
Số phát hành:
Vol 44 - N2
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
610
Ngôn ngữ:
Tiếng Anh
Từ khóa:
Cell cycle, cell viability, human fibroblast, senescence
Chủ đề:
Cell cycle
Tóm tắt:
This study aimed to assess the effects of simulated microgravity (SMG) on senescent human fibroblasts (HFs). The HFs were treated with 150 µM H2O2 in a culture medium for 90 minutes for senescent induction. The senescent HFs were induced SMG for 72 hours by a Gravity simulator, while the control group was treated in the same CO2 incubator. Cell morphology analysis showed that the SMG condition retrieved the fibroblastic morphology from the senescence. WST1 assay and cell counting indicated that the senescent HFs viability from the SMG group was higher than the control group (OD value of 0.80 ± 0.13 vs. 0.64 ± 0.11, respectively).