56471Reporting the impact of artemisinin resistance: Molecular surveillance of pfK13 and pfEXO mutations in Plasmodium falciparum in Southern provinces of Vietnam
Malaria, mainly caused by Plasmodium falciparum, is a major global health concern. In Vietnam, resistance to artemisinin-based combination therapies (ACTs) is rising, jeopardizing malaria control efforts. This study focuses on mutations in the pfK13 and pfEXO genes, particularly the E415G mutation, in Southern Vietnam. The study involved 421 patients across two cohorts. The first, with 63 patients from Binh Phuoc and Dak Nong, had uncomplicated P. falciparum malaria and were part of the Therapeutic Efficacy Studies (TES), treated according to WHO guidelines (2009). The second cohort, comprising 358 patients from the Central Highlands, aimed to assess mutation frequency in genes linked to artemisinin resistance. Molecular marker analysis, including Sanger sequencing for pfK13 and ARMS-PCR for E415G in pfEXO, was conducted. The study also examined the association of these mutations with Day 3 parasitemia and treatment outcomes using Dihydroartemisinin-Piperaquine (DHA-PPQ).
56472Reproductive/developmental toxicity screening test of kovir capsules in mice
The present study was performed to gather information on the effects of Kovir capsules on reproductive and developmental parameters in mice according to the OECD guideline for reproductive/developmental toxicity screening test. The test item was administered orally at dose levels of 1.44 and 2.16 capsules/kg body weight/day to male mice from 2 weeks before mating to the end of the 14-day mating period and females from 2 weeks before mating, during mating, gestation, and until the 13th day of lactation. During the study period, clinical signs, body weight, relative organ weight, reproductive and littering results, necropsy results, and histopathological examination of the testicles were examined.
56474Requirements engineering : 3rd ed.
Using the latest research and driven by practical experience from industry, Requirements Engineering gives useful hints to practitioners on how to write and structure requirements. It explains the importance of Systems Engineering and the creation of effective solutions to problems. It describes the underlying representations used in system modeling and introduces the UML2, and considers the relationship between requirements and modeling. Covering a generic multi-layer requirements process, the book discusses the key elements of effective requirements management. The latest version of DOORS (Version 7) - a software tool which serves as an enabler of a requirements management process - is also introduced to the reader here.
56475Requirements engineering : 4th ed.
Introduction. A generic process for requirements engineering. System modelling for requirement engineering. Writing and reviewing requirement. Requirement engineering in the problem domain. Requirement engineering in the solution domain. Advanced traceability. Doors: A tool to manage requirement. Management aspect of requirement engineering.
56476Requirements engineering : from system goals to UML models to software specifications
Shares state-of-the-art techniques for domain analysis,requirements elicitation, risk analysis, conflict management, andmore; Features in-depth treatment of system modeling in the specificcontext of engineering requirements; Presents various forms of reasoning about models forrequirements quality assurance; Discusses the transitions from requirements to softwarespecifications to software architecture.
56477Requirements engineering for software and systems
It provides a comprehensive review of current technology and developments in intelligent systems, soft computing techniques, and their diverse applications in manufacturing.
56478Requirements engineering: 2nd edition
Using the latest research and driven by practical experience from industry, this book gives useful hints to practitioners on how to write and structure requirements: Explains the importance of Systems Engineering and the creation of effective solutions to problems; Describes the underlying representations used in system modelling and introduces the UML2; Considers the relationship between requirements and modelling; -Covers a generic multi-layer requirements process; Discusses the key elements of effective requirements management; Explains the important concept of rich traceability; Introduces ...
56479Re-reading the salaryman in Japan : crafting masculinities
Introduction: salarymen in the 'Lost Decade'. Framing the 'macro': historicizing salaryman masculinity. Men's stories of becoming otoko. Becoming shakaijin: ' craftings' into salaryman masculinity. Working with salaryman masculinity. Working with heterosexuality: sexuality, marriage, fatherhood, and salaryman masculinity. Working with homosociality. Beyond the 'JTB-Man': looking back from the 2010s.
56480Reseaching factors affecting customer satisfaction when selecting services at resort sepon Quang Tri
Chapter 1: Introduction; Chapter 2: Theory Overview; Chapter 3: Research Methods; Chapter 4: Results and Discussions; Chapter 5: Conclusion.