21341Evolutionary characterization of clades 2.3.4.4 H5N6 and 2.3.2.1c H5N1 HPAI viruses in Vietnam (2013–2019) revealed distinct reassortants from distant spillovers
Highly pathogenic avian influenza (HPAI) H5Nx viruses have continually undergone multiple evolutionary dynamics for the generation of various clades, subclades, and genotypes where 2.3.2.2c, and 2.3.4.4 become predominant and co-circulating in Vietnam from 2014 to date. In this study, fifteen H5 sequences in our study and 90 from others from different clades, 0, 1, 1.1, 2.3.2.1a, 2.3.2.1c, 2.3.4, 2.3.4.1, 2.3.4.2, 2.3.4.3 and 2.3.4.4 of H5N1, H5N2, H5N6, were characterized for hemagglutinin (HA) properties, genetic and phylogenetic analyses. Blast searching using the dataset of the full length of two H5N6 viruses revealed one strain, e.g., A/Duck/Vietnam/HT7/2014(H5N6) in May 2014, belonging to the Sichuan 2014-lineage of Group D (Minor). The other strain, A/Chicken/Vietnam/NT3/2017(H5N6)/or CkNT3-2017 in the Spring of 2017, belonged to the Japanese-Korean late 2016-cluster of Group C (Major). This cluster possessed 140NHETS-145del stretch of Leucine/Serine deletion at position 145 in HA1 (S/L145del), distinct from all the 2.3.4.4 H5N6 viruses known to date. There has been no report of the similar CkNT3-2017 of 2.3.4.4 reassortant in Vietnam prior to our study. The migration flyway might be the route for transportation of this novel H5N6 virus from Japan to Vietnam. In addition, the topology revealed another novel subclade of H5N6 (2018–2019) possibly, of the Vietnamese internal reassortments. The “H5Nx” viruses in Vietnam, in fact, have continually undergone multiple evolutionary processes in parallel with those lineages in China and East-Asia. Variations at the key sites in HA and altered genetic characteristics in novel HPAI H5Nx viruses in Vietnam present a caution for the vaccination program and the risk for human infection.
21342Examination of the acute and subchronic oral toxicity of “Com Kien Ty” in experimental animals
Evaluate the acute and subchronic toxicities of “Com kien ty” through oral administration in experimental animals. The acute toxicity was determined using the Litchfield Wilcoxon method in mice. Following WHO's recommendation, the subchronic toxicity was assessed in rabbits with oral doses of 0.9 g/kg/day (equal to the recommended human dose) and 2.7 g/kg/day (3 times as high as the recommended human dose) in 4 consecutive weeks. Results showed “Com kien ty” at the highest dose of 60.0 g/kg did not express acute toxicity in mice. Regarding the subchronic toxicity test, after oral administration of “Com kien ty”, hematological parameters, hepato-renal functions were unchanged as compared with the control group, and no gross lesions in organs were observed in all experimental animals. In conclusion, “Com kien ty” did not produce acute and subchronic toxicities in Swiss mice and New Zealand rabbits.
21343Examining Japan's lost decades
This book examines five features of Japan's 'Lost Decades': the speed of the economic decline in Japan compared to Japan's earlier global prowess; a rapidly declining population; considerable political instability and failed reform attempts; shifting balances of power in the region and changing relations with Asian neighbouring nations; and the lingering legacy of World War Two. Addressing the question of why the decades were lost, this book offers 15 new perspectives ranging from economics to ideology and beyond.
21344Excel 2007 : giáo trình
Gồm 9 chương: 1. Các khái niệm cơ bản trong excel; 2. Thao tác định dạng; 3. Thao tác dữ liệu; 4. Các hàm cơ bản; 5. Các hàm cấu trúc điều khiển; 6. Cơ sở dữ liệu trên bảng tính; 7. Data table; 8. In ấn; 9. Vẽ biểu đồ;....
21345Excel 2007 formulas
Fully updated for the new release, this latest edition provides comprehensive, soup-to-nuts coverage, delivering over 900 pages of Excel tips, tricks, and techniques readers won’t find anywhere else. John Walkenbach, aka "Mr. Spreadsheet," is one of the world’s leading authorities on Excel. Thoroughly updated to cover the revamped Excel interface, new file formats, enhanced interactivity with other Office applications, and upgraded collaboration features. Includes a valuable CD-ROM with templates and worksheets from the book.
21346Excel functions & formulas in easy steps
Excel Functions and Formulas in easy steps shows you how to use the power of Excel functions and formulas to take full advantage of this popular spreadsheet application.
21347Excel kế toán và access kế toán
Gồm 2 phần: Phần 1: Excel kế toán và phần 2: Access kế toán.
21348Excel sales forecasting for dummies
Part I: Understanding Sales Forecasting and How Excel Can Help; Part II: Organizing the Data; Part III: Making a Basic Forecast; Part IV: Making Advanced Forecasts; Part V: The Part of Tens.
21349Excel Spreadsheets – Sự ứng dụng cho sinh viên khối kỹ thuật, phân tích kết cấu bằng phương pháp phần tử hữu hạn
Hiện nay có rất nhiều chương trình thương mại tổn tại để phân tích kết cấu bằng phương pháp phần tử hữu hạn, tuy nhiên một chương trình bảng tính như Microsoft Excel được giới thiệu nhằm mục đích đơn giản hóa đến mức có thể hướng đến những sinh viên không đủ nền tảng trong lập trình hoặc có vẻ miễn cưỡng để tìm hiểu nó. Phần mềm Excel được chọn để cung cấp một nền tảng lý tưởng về các tính toán số cũng như cách thức xử lý dữ liệu. Bài báo giới thiệu bảng tính Excel trong phân tích kết cấu dựa trên phương pháp phần tử hữu hạn.