The present study aimed to initially evaluate the anti-tumor effect of orally administered Saphia Alkali K90 in 7,12-dimethylbenz(a)anthracene (DMBA)-induced carcinogenesis in Swiss mice. Mice exposed to DMBA (total dose of 6 mg, p.o.) were treated with SAK90 at 15 ml/kg BW and 45 ml/kg BW daily. The vehicle was given to both normal and diseased controls. The change in body weight, mortality rate, tumor incidence, tumor burden, tumor yield, histopathology, and hematological and biochemical parameters were evaluated after 16 weeks of treatment.
Phatra Tricholes capsule is a multiplant production planned for dyslipidemia patients. Herein, we assessed the potential toxicity of Phatra Tricholes, applying the protocol of acute and sub-chronic oral administration in experimental animal models. According to the WHO guidelines, the acute toxicity study was conducted on Swiss mice.
“Dứa tre Lão nhà quê” extract (DTLNQ extract) was intended to treat several diseases such as dyslipidemia and venous insufficiency. To provide information on the its safety, this study evaluated the subchronic toxicity of DTLNQ extract. Wistar rats were divided into three groups and were given orally for 12 weeks. General conditions and body weight change, hematological and biochemical parameters, and hepatic and renal histological examinations were evaluated in treated rats compared with the control group and baseline.
Mui xoang Nhat Nhat (MXNN) spray is a herbal combination of Angelica dahurica, Xanthium strumarium L., Ageratum conyzoides L, which is intended to use as the supportive treatment of stuffy nose, runny nose in some upper respiratory diseases such as rhinitis and sinusitis. This study was carried out to evaluate the nasal mucosa irritation of MXNN spray in experimental animals.
This research was carried out to evaluate the acute and sub-chronic toxicity of ‘‘Huyet phu truc u hoan’’ (HPTUH) in experimental animals. The acute toxicity was defined on Swiss mice by the Litchfield – Wilcoxon’s method and the sub-chronic toxicity on Wistar rat’s hematopoietic function, liver, and kidney functions according to the World Health Organization Guidance.
This research aimed to evaluate the subchronic toxicity of Diabetna capsules through oral administration in experimental animals. The subchronic toxicity was studied in Wistar rats with oral doses of 0.72 g/kg/day (equal to recommended human dose) and 2.16 g/kg/day (3 times as high as recommended human dose) in consecutive 12 weeks, following guidance from the World Health Organization and Organisation for Economic Co-operation and Development.
This study aimed to evaluate the nutritional status and activities of daily living of older adults in a Vietnamese nursing home. A cross-sectional study included 100 older pepole aged ≥ 60 years old in a nursing home in Northern Vietnam in 2023.
This study was conducted to assess the prevalence of depressive symptoms among adolescents using the Birleson Depression Self-Rating Scale (DSRS) and to explore how demographic factors such as gender, grade level, and academic performance influence these symptoms. This is a cross-sectional study involving 996 students from two secondary schools in Hanoi, Vietnam. Participants completed the DSRS, and data were analyzedto calculate the prevalence of depressive symptoms. Associations between depressive symptoms and demographic factors were examined using odds ratios and regression analysis.
Sleep problems in healthcare workers during the COVID-19 pandemic have been studied extensively. However, little is known about insomnia in COVID-19-recovered healthcare workers. This study aimed to explore the prevalence of insomnia and its related factors among healthcare workers after COVID-19 infection in Vietnam. A cross-sectional study was conducted among 212 healthcare workers who had recovered from COVID-19 within 6 months and did not require hospitalization.
The study was conducted to investigate the clinical outcomes and mortality risk factors related to Staphylococcus aureus pneumonia in patients with and without diabetes mellitus (DM). This was a case-control study on 118 patients with S. aureus pneumonia hospitalized between April 2021 and May 2023.
