CSDL Bài trích Báo - Tạp chí
chủ đề: Cells
1 Evaluating the elimination of iCasp9-IL15 CAR-T cells using photosensitizers AP20187 in vitro / Can Van Mao, Le Duy Cuong // .- 2025 .- Tập 190 - Số 5E16 .- Tr. 20-25 .- 610
This study was conducted to evaluate the ability to eliminate iCasp9-IL15 Chimeric Antigen Receptor-T (CAR-T) cells using the photosensitizers AP20187 in vitro. Peripheral blood mononuclear cells (PBMC) were activated with Dynabeads Human T-Activator CD3/CD28 and IL-2 to optimize the concentration of the antibiotic blasticidin for screening iCasp9-IL15 CAR-T cells. iCasp9-IL15 CAR-T cells after proliferation with 1D2 artificial antigen-presenting cells, were screened using blasticidin. Subsequently, the iCasp9 suicide gene of these cells was activated at various concentrations of AP20187 photosensitizer.
2 Vitamin C inhibited fasl-induced apoptotic death of mouse dendritic cells through C-Flip expression / Nguyen Thi Xuan, Le Thi Thu Hien // Công nghệ Sinh học .- 2018 .- Number 16(4) .- P. 595-601 .- 610
The present study addressed the effects of vitamin C on survival of dendritic cells, a regulator of innate and adaptive immunity.