CSDL Bài trích Báo - Tạp chí
chủ đề: Obstetrics
1 Value of Non-invasive Prenatal Test (NIPT) for comprehensive fetal aneuploidies screening / Phan Hoang Cuc, Hoang Thi Ngoc Lan, Trinh Thi Que, Tran Hien, Nguyen Ba Son // .- 2024 .- Volume 184 E15 - N 11 .- P. 52-61 .- 610
The expanded NIPT for screening all fetal chromosomal aneuploidies has been widely used in clinical practice. The study was conducted on 6,104 pregnant women performing this test at Medlatec General Hospital to evaluate the values of NIPT.
2 ICSI and conventional IVF, which one should be prefered for cases of pre-implantation genetic testing? / Nguyen Thi Cam Van, Truong Van Hanh, Nguyen Thi Nhu Trang, Tran Tran Hue, Khuat Huu Quan, Le Thi Phuong Lan, Vu Thi Tho, Tran Thi Kim Lien // .- 2024 .- Volume 184 E15 - N 11 .- P. 130-139 .- 610
Ever since its implementation in 1992, the intra-cytoplasmic sperm injection (ICSI) technique has been hailed as a game-changer for enhancing the outcomes of in vitro fertilization (IVF) treatment in cases of infertility due to male factors. However, ICSI was later widely applied to cases of infertility not due to male factors without evidence proving its effectiveness. According to the 2022 report of the European IVF Monitoring Council (EIM), the rate of fertilization cases using ICSI method accounts for 70% of IVF cases in European countries, meanwhile the conventional IVF method accounts for only 30% and this rate has remained stable from 2006 until recently. The question is whether cases of infertility not due to male factors that are indicated for pre-implantation genetic testing (PGT) should be fertilized and create embryos using ICSI or conventional IVF to minimize invasiveness and reduce costs while still ensuring the accuracy of the test results.
3 Early diagnostis of splenic ectopic pregnancy: A case report and review literature / Pham Hong Duc, Pham Huu Khuyen // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 1-6 .- 610
Splenic ectopic pregnancy is extremely rare but carries a high risk of life-threatening intraperitoneal bleeding. Here, we present a 40-year-old woman presenting with vaginal bleeding. Although the intrauterine device (IUD) had been in place for 6 years, urinary and serum tests were positive for pregnancy. However, transvaginal ultrasound showed an empty uterus, no apparent adnexal masses or free fluid. An abdominal ultrasound was subsequently performed, which revealed a viable gestational sac in the spleen. An MRI that did not induce ionizing radiation was also performed, confirming the diagnosis of this splenic pregnancy. The gastrointestinal surgeon completed a laparotomy which successfully removed the spleen's superior pole containing an ectopic pregnancy.
4 Dydrogesterone-primed ovarian stimulation versus gnrh antagonist protocol in in-vitro fertilization for poor responders: A pilot study / Than Trong Thach, Nguyen Manh Ha, Le Hoang // .- 2024 .- Volume 177 E14 - N 04 - May .- P. 7-17 .- 610
This study aimed to evaluate the effect of PPOS protocol on the chance of success throughout the IVF process in patients with POR (POSEIDON group III & IV) undergoing IVF/ICSI in Vietnam. This was a randomized controlled trial involving 120 infertile women with POR. PPOS or GnRH-ant protocol was randomly applied to the participants of either group (n = 60 in each group).
5 Fetal - maternal hemorrhage: A comparison of two cases / Nguyen Thi Quynh Nga, Phan Thi Huyen Ninh, Pham Thao Nguyen // .- 2023 .- Tập 173 - Số 12 - Tháng 12 .- P. 249-256 .- 610
Almost all pregnancies have only a small amount of fetal blood in maternal circulation. In some rare cases, massive fetal-maternal hemorrhage can result in rapid fetal hemodynamic collapse, leading to severe fetal morbidity and mortality. Unfortunately, fetal – maternal hemorrhage is rarely diagnosed prenatally because clinical manifestations are often nonspecific, subtle, and difficult to identify at the time of the event. In this article, we present two cases of large fetal-maternal hemorrhage which were proven by the Kleihaure-Betke test to highlight the difference between nonspecific initial manifestations and the outcome of each case. Moreover, we would like to emphasize the importance of early detection and timely treatment to prevent potentially devastating complications of this condition.
6 Detection of pathogenic variants related to severe dominant monogenic diseases by non-invasive prenatal testing (NIPT-SGD) / Dao Thi Trang, Luong Thi Lan Anh, Nguyen Duy Anh, Nguyen Huu Duc Anh, Nguyen Thi Sim, Nguyen Thi Hao, Tang Hung Sang, Tran Vu Uyen, Nguyen Hoai Nghia, Giang Hoa // .- 2023 .- Tập 173 - Số 12 - Tháng 12 .- P. 1-8 .- 610
Report describes the first cases in Vietnam that identified pathogenic/likely pathogenic variants by NIPT-SGD in fetuses. These findings were compared with the diagnostic testing (whole exome sequencing/WES) on amniotic fluid/placenta tissue/umbilical cord blood samples. Single-gene NIPT detected pathogenic variants in the fetuses on TSC2, FGFR3, FGFR2 (two cases), and PTPN11 genes. All results coincided with the subsequent diagnosis. Preliminary research showed the potential of cell-free fetal DNA analysis for prenatal screening of dominant single-gene mutations.