Tóm tắt:

Screening inhibitors of α-amylase and α-glucosidase from medicinal plants is a topic of interest in the world. Canna edulis Ker Gawl is an important rhizome plant belonging to the genus Canna of the family Cannaceae. It is traditionally used to treat many conditions such as gonorrhea, pain, bruises, diarrhea, hepatitis, chest pain and heart diseases. The potential of this plant in the treatment and prevention of diabetes has rarely been documented. This study reports, for the first time, α-amylase and α-glucosidase inhibiting effects and the phytochemical profile of the rhizome part of C. edulis.C. edulis rhizome was extracted with 96% ethanol, and then successively fractionated with n-hexane, ethyl acetate and water. α-amylase and α-glucosidase inhibiting assays were performed to investigate the enzyme inhibitory activities of the total extract and fractions. Qualitative phytoconstituents were analyzed using chemical reactions.