Evaluation of acute and subchronic toxicity of An Nguyet Khang tablets in experimental animals
Tác giả: Nguyen Thi Nhu Quynh, Dam Dinh Tranh, Dinh Thi Thu Hang, Tran Thanh Tung
Số trang:
P. 37-46
Số phát hành:
Tập 173 - Số 12 - Tháng 12
Kiểu tài liệu:
Tạp chí trong nước
Nơi lưu trữ:
03 Quang Trung
Mã phân loại:
615
Ngôn ngữ:
Tiếng Việt
Từ khóa:
An Nguyet Khang tablet, acute toxicity, subchronic toxicity, experimental animals
Chủ đề:
Medicine
Tóm tắt:
The research evaluated the acute and subchronic toxicities of An Nguyet Khang tablets in experimental animals. Acute toxicity was defined by the method of Litchfield Wilcoxon in Swiss mice. The subchronic toxicity was evaluated by WHO and OECD's recommendation in Wistar rats with oral doses of 0.65 g/kg/day (equal to recommended human dose) and 1.95 g/kg/day (3 times as high as recommended human dose) in fourconsecutive weeks.